美国代写毕业论文:遗传机制

美国代写毕业论文:遗传机制

Zembrzyckiet al.(2015)的文章“遗传机制控制相关皮层初级和高级感觉区域之间的线性缩放”构成了本文的基础。在体内对初级视觉皮层的双向变化进行建模,以展示遗传机制的功能。

美国代写毕业论文:遗传机制

对于第一个问题,图3B显示了整个大脑ne-Emx2皮层V1和HO大小成比例的增加。从图中可以看出,ne-Emx2情况下V1和HO的大小与wt大脑相比更大。在3B的情况下使用了其他标记。另一方面,在4B的情况下,我们注意到,与wt相比,emx1 – ires – cres -介导的皮质特异性条件Emx2突变体的大脑V1和HO的大小成比例地减小。实验的结论是,在皮质区域模式的情况下,高阶没有固定的大小,初级感觉区域形成的顺序模型仍然很强。其次,作者能够确定,即使皮质表面积的主要区域大小因遗传因素而改变,主要和相关的较高区域仍然可能是成比例的。

美国代写毕业论文:遗传机制

The article of Zembrzyckiet al., (2015), ‘Genetic mechanisms control the linear scaling between related cortical primary and higher order sensory areas’ forms the basis for this essay. Bidirectional changes in primary visual cortex are being modelled in vivo in order to present the function of the genetic mechanisms.

美国代写毕业论文:遗传机制

For the first question, Figure 3B shows the proportionally increased V1 and HO sizes in the ne-Emx2 cortices of the whole brain. The figure shows that V1 and HO sizes in the case of the ne-Emx2 are larger when compared against the wt brains. Additional markers have been used in the case of 3B. On the other hand, in the case of 4B, it is noticed that there are proportionally decreased V1 and HO sizes in brains derived from Emx1-IRES-Cre-mediated cortex-specific conditional Emx2 mutant brains also referred to as the cBO when compared with the wt brains. The conclusion from the experiments was that in the case of cortical area patterning, the higher orders do not have a fixed size as such and the sequential model of primary sensory area formations are still strong. Secondly the authors were able to identify that even when the primary area size is altered by genetics in the cortical surface area, the primary and related higher areas might still be proportionate.